How to…

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  • Acknowledge the BRAINnet Database?


  • Refer to the Data?



Acknowledging the BRAINnet Database


BRAINnet Acknowledgments to use in publications and other forums


Acknowledgements in publication of papers

These acknowledgments should include:

  • Naming of BRAINnet and/or Brain Resource International Database in Abstract
  • Naming of BRAINnet and/or Brain Resource International Database in Key words where possible according to journal conventions
  • Inclusion in Acknowledgments section, using the following text format:

We acknowledge the data and support provided by BRAINnet; www.BRAINnet.net, under the governance of the BRAINnet Foundation. BRAINnet is the scientific network that coordinates access to the Brain Resource International Database for independent scientific purposes. We also thank the individuals who gave their time to participate in the database.

Acknowledgments in other public forums:

BRAINnet (www.BRAINnet.net) and the Brain Resource International Database should also be explicitly acknowledged in all other public forums which refer to the data and/or results from the data, including:

  • Conference presentations and posters
  • Talks, presentations and symposia
  • Websites of members, or other website forums

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Refer to the BRAINnet database?


Referring to the standardized Brain Resource methods

When referring to a dataset in any public forum, the relevant names for each Brain Resource platforms and methods must be used. These are:

  • Brain Resource IntegNeuro: The touchscreen battery used to assess general and emotional cognition, that is equivalent to the web-based version.
  • Brain Resource LabNeuro: Standardized protocols for assessing electrical brain function (EEG, ERPs) and concurrent body function (skin conductance, heart and respiratory rate, plus EMG).
  • BrainResource MolecularNeuro: Standardized protocols for acquiring swab, saliva or blood samples for genotyping, and in some datasets proteomics and metabolomics.
  • Brain Resource MRINeuro™: Standardized battery of structural and functional magnetic resonance imaging sequences.

Details on the standardized Brain Resource protocols and methods: Naming conventions for the individual assessments and items included in the standardized methods.

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WebQ – screening questionnaire

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The WebQ™ includes the following items:

Demographics

Disposition: Personal Details

  • Demographics (10 questions on DOB, sex, country of birth, marital status, height, weight, occupation, education x 2, ethnic origins

Disposition: Handedness/Laterality

  • Handedness (15 questions)

Medical history and psychological measures

Disposition: Medical

  • Vision, hearing, mobility/dexterity, mobile phone use learning/dyslexia, psychiatric/psychological, neurological, sleep x 2, eating, tobacco, alcohol, marijuana, recreational drugs, surgery, physical trauma) (16 trigger questions for optional sections 1 to 15)
  • Axis-I symptoms (SPHERES, draws on PHQ; 34 questions
  • Caffeine, Alcohol, Addictive Drugs (3 questions for harmful use)
  • Prescription medications (5 questions x max. of 3 medications)
  • Feeling and Self Regulation: Wellbeing and Personality Profile questions
  • Depression Anxiety and Stress Scale-21 (DASS-21; 21 questions)
  • BRIEF (Brain Resource Inventory of Emotional intelligence Factors; 14 questions)
  • NEO-FFI (NEO-Five Factor Inventory, 60 item)
  • BRISC (Brain Resource Inventory of Social Cognitions; 45 questions)
  • Environment: Stressors
  • Early Life Stress (19 questions)
  • Traumatic life events (11 trigger questions for optional sectional 16 on DSM trauma criteria)

Additional section (based on trigger questions)

Disposition: Medical (expanded from 16 trigger questions)

  • Vision (2 questions)
  • Hearing (2 questions)
  • Mobility/Dexterity (2 questions)
  • Mobile phone (4 questions)
  • Learning (difficulties/dyslexia; 5 questions)
  • Psychiatric/Psychological (8 questions)
  • Neurological (8 questions)
  • Sleep (A survey screen for prediction of Apnea, plus 16 questions on sleep disturbances)
  • Eating (disordered eating, Patient Health Questionnaire, 7 questions)
  • Tobacco-Smoking (Fagerstrom Test for Nicotine Dependence, 6 questions)
  • Alcohol (AUDIT WHO Alcohol Use Disorders Identification Test, 10 questions)
  • Marijuana (3 questions)
  • Recreational Drugs (2 questions)
  • Surgery (3 questions)
  • Physical Trauma (7 questions)
  • Traumatic experiences (DSM-IV Criterion A trauma, 30 questions)

IntegNeuro

The IntegNeuro™ battery includes the following tasks for general and emotional cognition.

These domains provide disorder-specific assessments. For instance, they correspond to the domains of MATRICS MCCB for schizophrenia.

Brain Resource naming conventions for these tasks are as follows:

Thinking

  • Motor Tapping
  • Choice Reaction Time
  • Verbal Memory Recall (including delayed conditions)
  • Time Estimation
  • Spot The Real Word
  • Word Generation
  • Span of Visual Memory
  • Digit Span (Forwards and Reverse)
  • Verbal Interference (Parts 1 & 2)
  • Switching of Attention (Parts 1 & 2)
  • Maze
  • Go/NoGo
  • Continuous Performance Test (n-back)

Emotion

  • Emotion Identification (explicit)
  • Emotion Recognition (implicit, delayed)

WebNeuro

The WebNeuro battery includes the following tasks for general and emotional cognition.

These domains provide disorder-specific assessments. For instance, they correspond to the domains of MATRICS MCCB for schizophrenia.

Brain Resource naming conventions for these tasks are as follows:

Thinking

  • Motor Tapping
  • Choice Reaction Time
  • Verbal Memory Recognition (including delayed conditions)
  • Span of Visual Memory
  • Digit Span
  • Verbal Interference (Parts 1 & 2)
  • Switching of Attention (Parts 1 & 2)
  • Executive Maze
  • Go/NoGo
  • Continuous Performance Test (n-back)

Emotion

  • Emotion Identification (explicit)
  • Emotion Recognition (implicit, delayed)

LabNeuro

The LabNeuro™ battery includes the following assessments for brain and body functions.

Assessment include electrical brain function (EEG, ERPs) and concurrent body function (skin conductance, heart and respiratory rate, plus EMG).

Brain Resource naming conventions for these tasks are as follows:

  • Resting (Eyes Open)
  • EEG, body function
  • Resting (Eyes Closed)
  • EEG, body function
  • Habituation
  • Body function
  • Smooth Pursuit Eye Tracking EMG
  • Auditory Oddball ERPs, body function
  • Go/No-Go ERPs, body function
  • Continuous Performance Test (CPT, with sustained attention and n-back condition); Working Memory ERPs, body function
  • Novelty task (checkerboard stimulus)
  • Startle (with Startle and Prepulse Inhibition conditions) EMG, Body function
  • Facial Expressions of Emotion (unmasked, conscious) ERPs, body function
  • Facial Expressions of Emotion (masked, nonconscious) ERPs, body function

MolecularNeuro

SNPs currently available are listed below. A further 300 SNPs are due to be completed by October 2009 (including neuregulin and genes shown to impact synaptic and hormonal function)*

First 20 SNPs are:

  • Apolipoprotein E, APOE
  • Abnormal spindle-like, microcephaly-associated (A44871G – refers to genomic DNA sequence; amino acid change is S2562G), ASPM Brain derived neurotrophic factor (val66met), BDNF
  • Cathepsin D (224C>T) (A58V), CTSD
  • Catechol-O-methyltransferase (val108/158met), COMT
  • Dopamine receptor type D2 (-141C Ins/Del), DRD2_1
  • Dopamine receptor type D2 (957C>T), DRD2_2
  • Dopamine receptor D4 (-521C>T), DRD4_2
  • Dopamine beta hydroxylase (-1021C>T), DBH
  • Dopamine transporter (40-bp VNTR), DAT1
  • Dopamine D4 receptor (48-bp VNTR), DRD4
  • Histamine N-methyltransferase (314C>T), HNMT
  • Microcephalin (G37995C – refers to genomic DNA sequence; amino-acid change is D219H), MCPH1
  • Monoamine oxidase A (30-bp VNTR), MAOA
  • Serotonin receptor 1A (-1019C>G), HTR1A
  • Serotonin receptor 2A (-1483A>G), HTR2A_1
  • Serotonin receptor 2A (H452Y), HTR2A_2
  • Serotonin receptor 3A (C178T), HTR3A
  • Serotonin transporter (44-bp DIP), 5HTT
  • Succinate-semialdehyde dehydrogenase (538C>T) (H180Y), ALDH5A1

* Contact brainnet@brainresource.com for further information on these additional SNPs

MRI-Neuro

The functional and structural MRI sequences and their Brain Resource naming conventions are as follows:

  • MPRAGE sequence for grey and white matter volume. Data available in numeric form for both grey and white matter for 106 brain regions based on standardized atlas
  • DTI sequence for brain connectivity
  • Auditory Oddball Functional MRI sequence*
  • Go/No-Go Functional MRI sequence*
  • Continuous Performance Test (CPT, n-back); Working Memory Functional MRI sequence*
  • Facial Expressions of Emotion (unmasked, conscious) Functional MRI sequence*
  • Facial Expressions of Emotion (masked, nonconscious) Functional MRI sequence*

*Image data not part of standard BRAINnet database. Contact brainnet@brainresource.com in regard to these datasets.