BRAINnet - data request
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Brain Research And Integrative Neuroscience Network

How to I propose a paper to BRAINnet to access BRID?

On becoming a BRAINnet member, you will receive a copy of the BRAINnet guidelines for proposing a new paper and requesting data. These requests are made via the internet using the BRAINnet website.

When first submitted, paper proposals can not be viewed on the external website. They will be viewed only once confirmed – and are then listed with other confirmed projects under the research/projects menu.

As a member, you would login and submit a paper proposal – equivalent to an extended abstract.

This proposal is checked for feasibility by the BRAINnet coordinator (eg. confirmation the scores are available to BRAINnet and the proposal does not overlap with another already underway). The proposal is then circulated by email to all relevant members of BRAINnet and (often inclusive) at least one member at each organization/lab. involved in BRAINnet. Responses must come back within 2 weeks, and address a) scientific soundness of project (any vetos must be sent by reply all to other members), b) appropriateness of any other members involvement as co-author and c) suggestions for refinement. Vetos may also be based on overlap with existing projects if missed by BRAINnet coordinator.

(To date, proposals have been vetoed on the basis of data not available, and in only 1 case, scientific quality).

How to I request data from BRID?

Once a proposal is confirmed, the BRAINnet member may request the relevant data from BRID. It is important to note that:

BRAINnet members receive scored data only, and that original raw datasets are owned by BRC.

Approval to use scored data is on a paper by paper basis. BRAINnet members must not keep datasets and reuse for a later paper without submitting a new proposal through BRAINnet.

BRC makes scored data in BRID available to BRAINnet on the understanding that these conditions are met – and that BRID is acknowledged in the paper.

Data requests are also made via the BRAINnet website, and will be linked to your paper proposal. Requests are processed monthly (but can take longer for complex requests, such as those involving intricate matching to normative data). BRAINnet is updating its web-based request system, so that members will have a user-interface to directly select the measures required by the paper.

Once collated, scored data are either downloaded from the web request system, or sent by email. In each case, conditions of use must be accepted.

Brain Resource Testing Platforms

The BRID has been acquired using BRC's standardized and computerized testing platforms. These testing platforms are also available as testing products available for applications in clinical trials, clinical management and peak performance settings. For these applications, specific reports are generated to interpret performance relative to the BRID normative database. In addition, BRC offers a ‘Discovery' product which is the use of these testing platforms for not-for-profit scientific research (see ‘Discovery' product below).

Information on testing platforms is available at www.brainresource.com (see products menu), and a summary of this information follows:

•  WebQ (Web Questionnaire) – an internet-based battery assessing illness features and psychological function. Can be used for assessing inclusion/exclusion criteria and specific aspects of wellbeing. Includes symptom measures, and assessment of substance dependence, emotional intelligence and regulation, and stressful life events.

•  IntegNeuro - a touchscreen based neuropsychological test battery for assessing general and social cognition, validated against traditional paper-and-pencil tests and with established reliability, cross-cultural consistency and norms

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IntegNeuro - delivered via IBM Touch screen

 

•  WebNeuro – a web-based version of IntegNeuro, with established validity between these platforms

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WebNeuro -delivered via PC and Internet.

 

•  LabNeuro - Standardized assessment of EEG, event-related potentials (ERPs) and concurrent autonomic measures (heart rate, skin conductance) during both resting and task activation conditions. Tasks include habituation, oddball, working memory/sustained attention, Go-NoGo, startle PPI, and facial emotion perception.

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LabNeuro - bringing together central and autonomic nervous system measures in the Lab

•  MR_Neuro – Magnetic Resonance (MR) imaging data acquired using MPRage and Dual Echo sequences to provide high resolution information on brain anatomy. In addition, functional MR data acquired during activation tasks which correspond to those used with ERPs – for oddball, working memory/sustained attention, Go-NoGo and Emotion perception.

•  GenomiNeuro – Collection via saliva method (and in some cases bloods) of DNA for extraction of SNPs and other variants of interest which impact neurocognition.


How can I use Brain Resource Testing Platforms for ‘Discovery' research?

BRC also provides a Discovery option, so that its testing platforms can be used in new not-for-profit research projects. The data acquired from these projects is clearly owned by the relevant investigator. However, investigators may choose to add their data to the BRID. In this instance, further discounts on testing may be available. In addition, it opens up other opportunities to the investigator(s): for instance, the comparison of their dataset on say, schizophrenia, with other datasets acquired using the identical tests, with depression or bipolar disorder and the increase in potential publication outcomes. In this case, the investigator(s) right of first access to the data is supported in two ways: 1. the Discovery contract would include agreement to not release the investigator(s) data into the BRID until a fixed period of time (typically the duration of the project), and 2. if release to the BRID encompasses release to BRAINnet, then the BRAINnet guidelines would apply. Any potential publication including a proposal to use these data would be circulated to relevant BRAINnet members (including of course the investigator(s)), and these members have the right of veto. For these proposals, the original investigator(s) would be eligible for nomination as co-author and thereby gaining additional publication outcomes from the data used in new ways.