| Title: |
Neurophysiological Modelling of Corticothalamic Dynamics in the Waking EEG |
| Research Area(s): |
ADHD and Allied Conditions |
| Background: |
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| Aims: |
A computer model of EEG activity in the brain is outlined providing a unified and testable explanation of the major EEG rhythms in different states of arousal. The model incorporates macroscopic intracortical, cortico-cortical and corticothalamic pathways, and microscopic neural properties including synaptic activation, separate excitatory and inhibitory connections, dendritic propagation, firing thresholds and axonal conduction. |
| Method: |
To test the model and determine its neurophysiological parameters the model’s linear spectrum was fitted to the EEG data of 100 normals in relaxed eyes-closed and eyes-open states. A paired samples t-test was used to ascertain which cortical parameters varied significantly between the two states, and a correlation matrix was used to compare the model parameters to traditional measures of QEEG for slow wave, delta, theta, alpha, beta and gamma band powers. |