Predicting stimulant medication response in ADHD

Proposal details

Title: Predicting stimulant medication response in ADHD
Research Area(s): ADHD and Allied Conditions
Background: Predicting stimulant medication response in ADHD: evidence from an integrated profile of neuropsychological, Psychophysiological and clinical factors
Aims: There have been significant advances in understanding the neurobiology of ADHD and it is timely to examine the ability of biological and psychological markers to predict medication response in this disorder. We evaluated prediction of medication response in adolescent ADHD using neuropsychological testing and psychophysiological measures of central and autonomic function.
Method: Fifty ADHD adolescents participated in pre- and post-stimulant medication testing. Separately ranked performance in auditory oddball and visual working memory (WM) tasks determined 20 responders and 20 non-responders, with 10 neutrals excluded from the discriminant function analyses (DFA).