Alzheimer's and WMH
Proposal details
| Title: | White matter hyperintensities and Alzheimer disease |
|---|---|
| Research Area(s): |
Brain Imaging Thinking and Cognition |
| Background: | White matter hyperintensities are areas of increased lucency visualized on T2-weighted MRI scans. These areas are thought to reflect small vessel cerebrovascular disease and are related to cognitive abilities in older adults. Recent literature has supported a specific role of WMH in Alzheimer's disease, and although a non-specific marker, examination of the distribution of WMH may help further elucidate mechanisms linking them to Alzheimer's disease. |
| Aims: | This project seeks to examine the regional distribution of WMH in patients with AD and controls and to examine cognitive correlates |
| Method: | We will compare lobar distribution of WMH between AD patients and contorls and examine relationships with cognition. |