Phenibut: Reviews, Dosage, Effects & Where to Buy Powder


It can be easy to become stressed out in our hectic lives. We spend so much time running around doing various tasks that we forget to pay attention to our mental health. Because of this many of us have feelings of anxiety and depression in our lives that make it difficult for us to live a fulfilling life. 

To combat these feelings, a lot of people use supplements like nootropics to relax their minds. Although there are a ton of popular nootropics like Modafinil and Mind Lab Pro on the market most of these are used to increase focus and energy levels. However, if you’re looking for a nootropic that was specifically created to lessen some symptoms of anxiety, then Phenibut is the one you need. 

This nootropic was created as a nootropic to boost cognitive functioning. It has been shown to help people deal with anxiety and also provide a euphoric effect. Although this drug is not very widely used, it has been around for quite a long time. 

But how do you figure out if this product is right for you? 

This article will help you to solve that issue. We’re going to give you a rundown of all the benefits of Phenibut as well as all the cons. We’ll also tell you how you can decide which dosage is best for you. 

Let’s get started with a quick introduction to this product. 

What Is Phenibut?

Phenibut is a Russian drug that has been used as a medication for social anxiety. This drug was first developed in the 1960s as a nootropic to help boost cognitive abilities. It was created under the Soviet Union and was eventually distributed as a medical supplement. Although Phenibut is a synthetic nootropic, this drug is less harsh than some other drugs like Modafinil. 

Although further research still needs to be done on this drug, it is clear that it has a calming effect on the brain[1]. Phenibut was designed to be very similar in structure to a particular neurotransmitter known as Gamma-Aminobutyric acid or GABA. By mimicking the structure of GABA, Phenibut is able to relax the mind and keep it calm. This improves the alertness and focus of a person’s brain[2]. It can also help to reduce the amount of brain fog. 

So now that we know the effects of the drug let’s look at the mechanism behind it. 

How Does It Work?

Nootropics are drugs that change the way that the brain works. They do this by altering the levels of certain neurotransmitters in the brain. Phenibut also works in a similar way. 

The structure of Phenibut is an analog to GABA[3]. It is also known by its chemical name β-phenyl-GABA. The chemical structure of Phenibut has a phenyl ring added to the regular GABA chemical structure which is why it got its chemical name. Although the structure of Phenibut is slightly different from GABA both of these compounds function in a similar way. 

When Phenibut is consumed, it activates the GABA receptors in the brain[4][5]. This helps to calm the mind and reduce feelings of anxiety[6]. There is also some evidence that shows that Phenibut helps to increase dopamine in the brain. This also plays a role in improving the mood of a person. 

What Is It Used For?

This nootropic is a bit different from other nootropics because it is primarily used as a therapeutic supplement for anxiety. Many nootropics are marketing as energy-boosting supplements that can help you to work for hours. However, Phenibut was meant to relax the mind and get rid of feelings of frustration and stress. 

Therefore Phenibut is mainly used by people who tend to have feelings of frustration and anxiety. This is especially useful for individuals who have stressful jobs and have to meet tight deadlines. This drug is not used by students generally and is not great for long hours of work. However, if you need to calm your nerves then Phenibut is your best bet. 

Most countries do not need a prescription for purchasing Phenibut which is probably why so many people view this as a supplement. This makes Phenibut a very useful nootropic. 

Effects & Benefits

The primary benefit of Phenibut is that it is able to calm the brain and enhance the mood of an individual. These effects help to make this drug the perfect anti-anxiety medication. However, there are also a few other benefits which we will discuss below. 

Anti-Anxiety Treatment

Phenibut was created to act as an anti-anxiety medication. Because of the increase of GABA in the brain, the GABA receptors in the brain are activated. This helps to keep the mind calm and relaxed. 

So when should you take Phenibut? Anxiety is typically associated with feelings of fear and embarrassment. If you’ve ever been to a new workplace or a new school and felt nervous about interacting with strangers then you’ve felt anxiety before. Phenibut is meant to act as a calming drug in these situations[7]. 

When a person is experiencing daily feelings of severe anxiety and depression on a daily basis, they are often dealing with an illness. These feelings can have a massive impact on your life and prevent you from carrying out basic activities. In this case, it is recommended that you seek professional help from a therapist who will guide you on what steps you can take to improve your life. We also recommend having a look at the nootropics that work for anxiety and depression.

Although Phenibut has been shown to help reduce many symptoms of anxiety, it cannot be used on a daily basis. Therefore it should be used along with other therapeutic methods for people who suffer from an anxiety disorder. We recommend that you contact a medical professional if you intend to use Phenibut as a medication. 

However, this drug is useful for calming nerves and giving users a euphoric feeling to ward off general feelings of anxiety. 

Cognitive Enhancement

By reducing stress and relaxing the mind, Phenibut is also able to boost cognition in individuals. When you’re stressed it can become tough for you to focus on anything. This causes your productivity to suffer and it can make it difficult for you to work well. 

When Phenibut attaches to the GABA receptors, it is able to calm to mind and clear out brain fog. This aids in cognitive enhancement and allows you to work faster and better than before.  It can also improve focus and boost your alertness. There is also evidence that shows that Phenibut might increase the amount of dopamine in your brain. Dopamine is associated with better mood and overall happiness.

Sleep Aid

One persistent and damaging symptom of anxiety is insomnia. When your mind is full of stress and anxiety-filled thoughts it is very difficult to get a good night’s rest. Phenibut calms the mind and gives you a euphoric feeling. This is because of the GABA receptors that it activates in the brain and also due to the release of dopamine. By doing this, Phenibut is able to soothe the brain into a state of rest. 

Dosage & How to Take

Everyone’s body is different and therefore you must tailor your dosage according to your experience with this nootropic. However, people usually tend to take around 250 gms to 500 gms daily. 

This drug should not be used on a daily basis so most users will take Phenibut for around 2 to 3 days and then wait around 4 days before repeating the dosage. This will also make sure that your body is not getting resistant to the drug. Phenibut can also be cycled with other drugs which is good for people who tend to use nootropics daily. A single dose will give you around 4 to 6 hours of activity depending on how much you have consumed.

We recommend beginning with a small dose to learn how your body copes with it. Then you can increase the dosage as you see fit. 

Side Effects

Phenibut is a synthetic nootropic which means that it can be quite potent. Small amounts of this drug can go a long way to relaxing the mind. It can improve mental clarity and decrease some symptoms of anxiety like stress. 

However, there are also a few downsides to this drug. Due to the nature of Phenibut, this drug should be taken with caution. Taking too much of this drug can cause adverse side effects like irritability, drowsiness, dizziness, headaches and other side effects[8].  

Taking excessive amounts of GABA can also worsen certain symptoms of anxiety. Large amounts of GABA can worsen the symptoms of anxiety and make people more irritable. It can make people jittery and nervous. There are also some users that have experienced sleepiness after taking these drugs. 

Generally, these side effects are quite rare and do not occur unless the normal dosage is exceeded. However, it’s always good to be cautious while taking these drugs. Start out with a small dose and then work your way up. 


One other downside of Phenibut is that it causes dependency in individuals. Some users have said that they have experienced symptoms of withdrawal once they stopped using this drug regularly. These symptoms can include nausea, headaches, dizziness, and other similar symptoms. 

If you want to stop using Phenibut then you will have to gradually reduce the amount of Phenibut that you take until you eventually stop. By tapering off your doses you will be able to avoid all the symptoms of withdrawal. 

Symptoms of addiction may include, craving the product at all times and experiencing adverse effects after missing a dose or two. If you experience these symptoms then immediately begin to reduce the dosage you are taking and seek help from a medical professional. 


An overdose usually happens when you take a drug dose that is too much for your body to handle. This can result in severe damage to your body. To avoid an overdose it is important to keep your dosage as small as possible. Remember to stay within the dosage limits and you will not experience this. 

Experiences Shared on Reddit

Reddit is the perfect place to get unfiltered reviews about any product under the sun. So what does Reddit think of Phenibut?

The majority of the reviews are positive however some people did not get the result they were hoping for. Some individuals find that Phenibut is by far the best nootropic drug they have used for anxiety. Others feel like the drug isn’t as powerful as some other alternatives or did not meet their needs. There have also been reviews of a few unpleasant side effects. 

Best Phenibut Stacks

When we talk about stacking it usually refers to using two or more nootropic substances along with each other. Most common nootropic supplements on the market are made by stacking multiple substances together. 

Phenibut stacks well with a variety of nootropics and nootropic substances but should be used with caution. 

Stack for Mood and Anxiety

This drug might increase the effects of other nervous system depressants. Thus nootropics which relax the mind like Bacopa Monnieri are great for stacking. You can vary your dosages according to your preference. 

Stack for Athletic Recovery

If you are looking for nootropics that help to boost recovery then supplements like L-theanine are very useful. They start well with Phenibut and relax the mind while also helping your body to recover from strenuous activity. 

Where to Buy Phenibut?

Phenibut is used primarily as a medical supplement and does not need a prescription to be purchased in many countries. However, there are some countries like Italy, France, and Lithuania that classify Phenibut as a controlled substance. This means that you might need a prescription to purchase Phenibut in some countries. 

However, in most countries, you can purchase Phenibut as an over-the-counter drug from many places. There are also a few online stores like Science Bio that offer Phenibut. Before buying this drug ensure that you are purchasing it from a trusted vendor. The best way to figure this out is to buy from shops that are recommended by people who regularly use nootropics. Online communities like Reddit will also help you to get more options to buy Phenibut from. 

Frequently Asked Questions (FAQ)

How Long for Phenibut to Kick In?

It will begin to work around 2 or 3 hours after it is consumed.

How Long Does It Last?

This drug works for around 5 hours.

When Does Withdrawal Start?

For most drugs including Phenibut, withdrawal tends to start around 24 hours after the last dose. 

How Long Does Withdrawal Last?

Generally, withdrawal symptoms can last for multiple days. 

How Long Does It Stay in Your System?

This drug typically lasts around 5 hours and the elimination time is around 26 hours.

How Often Can You Take It?

It is recommended to take this drug around 2 to 3 times a week. 

Does It Help with Sleep?

Phenibut is not as effective as sleeping pills that were designed to reduce insomnia. However, this drug still helps to induce sleep. 

Does It Really Work for Anxiety?

After looking at the research and many online reviews we can say that yes, this supplement helps to reduce symptoms of anxiety. 


We’ve gone over a ton of information in this article so let’s summarize everything. Phenibut is a GABA analog that helps to relax the mind. It is meant to be used primarily as a therapeutic supplement for anxiety. 

The benefits of this supplement are that it provides consistent results that are backed up by many online reviews and studies on this drug. It is able to reduce symptoms of anxiety and is extremely useful for people who experience these feelings. 

On the other hand, the side effects associated with Phenibut are quite harsh. Taking too much of this drug can also cause addiction and eventually lead to withdrawal symptoms. Additionally, the effects last for around 5 hours. 

If you want an anti-anxiety drug that you can use around 2 or 3 days a week then Phenibut is for you. However, if you want a daily nootropic or if you want something more powerful then other nootropics like Mind Lab Pro and Modafinil might be better. 


  1. Lapin I. (2001). Phenibut (beta-phenyl-GABA): a tranquilizer and nootropic drug. CNS drug reviews, 7(4), 471–481.
  2. Kratom and Phenibut: A Concise Review for Psychiatric Trainees, Monique Mun and Andrew Wong, American Journal of Psychiatry Residents’ Journal 2020 16:2, 6-8
  3. National Center for Biotechnology Information (2021). PubChem Compound Summary for CID 14113, 4-Amino-3-phenylbutanoic acid. Retrieved October 10, 2021 from
  4. Zyablitseva, E. A., Kositsyn, N. S., & Shul’gina, G. I. (2009). The effects of agonists of ionotropic GABA(A) and metabotropic GABA(B) receptors on learning. The Spanish journal of psychology, 12(1), 12–20.
  5. Shul’gina, G. I., Petrishcheva, A. P., & Kuznetsova, G. G. (1985). Vliianie proizvodnogo GAMK–fenibut na povedenie i aktivnost’ neĭronov zritel’noĭ kory krolikov pri vyrabotke oboronitel’nogo refleksa i vnutrennego tormozheniia [Effect of a derivative of GABA, phenibut, on behavior and the activity of visual cortex neurons of the rabbit during elaboration of a defensive reflex and internal inhibition]. Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova, 35(4), 695–702.
  6. [The effect of GABA derivative phenibut on defensive conditioning and internal inhibition], Ziablintseva E. A. (2006). Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova, 56(2), 236–241.
  7. Zyablitseva, E. A., & Pavlova, I. V. (2008). Effects of the GABA receptor agonist phenibut on behavior and respiration in rabbits in emotionally negative situations. Neuroscience and behavioral physiology, 38(6), 555–562.
  8. Owen, D. R., Wood, D. M., Archer, J. R., & Dargan, P. I. (2016). Phenibut (4-amino-3-phenyl-butyric acid): Availability, prevalence of use, desired effects and acute toxicity. Drug and alcohol review, 35(5), 591–596.
Erica Bail

Having specialized as a Neurologist for 8+ years treating patients with diseases like Parkinson's disease, Sclerosis, Dementia and Brain Injury. Dr Erica has the passion and experience to detect, diagnose and manage any type of brain disorder.

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